
Normal appearance

During cutaneous attack: Nonpitting edema
If left untreated or inadequately controlled, at least 3 in 4 attacks were severe enough to negatively impact quality of life, according to nearly 86% of patients, many of whom were using a preventive therapy.1
97% of patients agree nothing can be more convenient than the medication that sets them free from worrying about HAE attacks.2
* These findings are the result of an online survey conducted by The Harris Poll, sponsored by CSL Behring Inc, involving 100 U.S. adults ages 18+ who have been diagnosed by a healthcare professional with Hereditary Angioedema (HAE) (“people living with HAE”); and 150 licensed Allergists/Immunologists in the U.S. who have treated/managed at least 2 HAE patients in the past 12 months (“physicians”).
C1-INH=C1 inhibitor.
HAE=hereditary angioedema.
† The plasma levels of C1-INH functional activity were evaluated in patients with type 1 or type 2 HAE in a Phase 3, placebo-controlled, crossover study. Patients received twice-weekly subcutaneous injections of HAEGARDA 40 IU/kg or 60 IU/kg for 16 weeks. The model-derived outcome is the steady-state C1-INH functional activity vs time.4
The World Allergy Organization (WAO) guidelines recommend the use of C1-INH for HAE for long-term prophylaxis.11
HAEGARDA is the HAE product that reduced HAE attacks by 95%.‡
LEARN MORE‡ Median reduction in the number of attacks with HAEGARDA 60 IU/kg vs placebo.
§ Short-term or preprocedural prophylaxis can also be administered before an event that may trigger an HAE attack (eg, medical or invasive dental procedure).
World Allergy Organization/European Academy of Allergy and Clinical Immunology
guidelines on prophylaxis
"We recommend that patients are evaluated for long-term prophylaxis at every visit. Disease burden and patient preference should be taken into consideration. Evidence Grade D; strength of recommendation strong, 100% agreement."
Normal appearance
During cutaneous attack: Nonpitting edema
Normal appearance
During laryngeal attack: voice change, hoarseness, swelling of larynx
Normal appearance
During abdominal attack: gastrointestinal pain, nausea, vomiting, swelling of abdomen